College of Natural and Computational Sciences

Lei WangLei Wang, Ph.D.

Assistant Professor of Chemistry

Phone: 808-236-5836
Office: 217 AC, Hawaii Loa campus
Website: Google Scholar – Lei Wang
                  Research Group

Education: B.S., Physics, Wuhan University; Ph.D., in Biophysics, Brown University; Post-doctoral Fellowship, The Salk Institute for Biological Studies; Post-doctoral Fellowship, Swiss Federal Institute of Technology Zurich (ETH Zurich)

Professional Interests: Protein folding and aggregation in human diseases; protein engineering in bio-nanotechnology

Courses: CHEM 2050 General Chemistry I; CHEM 4031 Biochemistry Lab I; CHEM2052 General Chemistry II; CHEM4095 Biochemistry Seminar

Personal Interests: Traveling, running, hiking, swimming, diving, surfing, skiing, and most importantly, my family

Research Interests

Dr. Wang’s major research interest is protein aggregation, which is involved in more than a dozen of human diseases, such as Alzheimer’s disease, Parkinson’s disease and Cataract. His research group studies several disease-related protein aggregation events, tries to understand their underlying molecular mechanism, and aims to identify effective natural compounds that can interfere with protein aggregation processes to prevent or delay disease onset. For example, his group is interested in studying the protein aggregation mechanism in (a) human memory loss, (b) cataract and human lens clarity, (c) obesity and regulation of food intake. Dr. Wang is also interested in developing bio-nano material by using a special type of protein aggregates, amyloid fibrils, which are genetically modifiable natural bio-nanowires.