College of Natural and Computational Sciences

Andrew Brittain, Ph.D.

Education

B.S., 1978,  Biology with Marine Options Certificate. University of Hawaii at Manoa Ph. D., 1993,  Microbiology, University of Hawaii at Manoa

National Research Council Fellow May 1993-May 1996, at Marshall Space Flight Center studying nutrient cycling of closed ecosystems with stable isotopes and production of recombinant proteins for micro-gravity crystallization studies.

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Patents

Brittain, A. "Yeast-toxin-related protein for antimicrobial vaccine and sterilizing preservative use."  US-5969098, Oct. 19, 1999 / June 6, 1997. CyberChemics, Inc., Huntsville, AL

Brittain, A. "Antimicrobial Peptides." US-5,981,698, Nov. 9, 1999 / June 3, 1997. CyberChemics, Inc., Huntsville, AL

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Service

External service has been directed to leadership roles in two non-profit organizations and volunteer work with a third.  I have been a board member for on the Hawaii Academy of Science helping to direct that organization in promoting science education, largely through the statewide science fairs.  I have been a board member of the Kailua Bay Advisory Council for the last four years helping to direct that organizations efforts at improving environmental water quality on the windward side.  I have also assisted the Friends of He’eia in many initiatives which are described best as scholarship but which are also service.

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Publications

D.A. Noever, H. Matsos, A. Brittain, (1997) Genetic Algorithm Application. Biosystems, vol.39, 2.

R.J. Cronise, D.A. Noever,  A.M. Brittain, (1996) Self organized criticality in closed ecosystems: carbon dioxide fluctuations in Biosphere II. International Journal Of Climatology, vol. 16 (1-6).

D. A. Noever, A. B. Brittain, H. C. Matsos, D. C. Obenhuber, R. Cronise, S. Armstrong, (1996) Microbial diffraction grating as optical detectors for heavy metal pollutants: in press Review of Scientific Instruments.

D.A. Noever, H. Matsos, A. Brittain, D. Obenhuber, Subbiah Baskaran, (1996) The effects of variable biome distribution on global climate. Biosystems, 26,2-7.

A. M. Brittain, J.A. Shaffer, The niche for biosphere science: A research agenda for a thermodynamic approach to closed ecological systems. Conference Proceeding of the 2nd International Conference on Life Support and Biospherics, 1994, University of Alabama Huntsville Alabama.

A. B. Brittain,  The steady state behavior and variability of closed ecosystems. Conference Proceeding  of  the 2nd International Conference on Life Support and Biosphere Sciences. 1994, University of Alabama, Huntsville Alabama.

A. M. Brittain, The metabolic diversity, biological activity and stability of the steady state condition in closed ecological systems. 1993 Ph.D. D Dissertation, University of Hawaii, Honolulu Hawaii.

D. C. Obenhuber, J. Shaffer, A. Brittain. Recent Developments in the study of closed ecosystems. Conference Proceeding of the International Conference on Life Support and Biospherics, 1992, University of Alabama Huntsville Alabama.

G.Tien, L. Asato, A. M. Brittain , D. F. Bird, R. Letelier, D. M. Karl, RACER: Plankton rate processes in the northern Gerlache Strait, 1989-1990. Antarctic Journal of the U.S. vol 25:152-154.

A. B. Brittain, D. M. Karl 1990. Catabolism of tritiated thymidine by aquatic microbial communities and incorporation of tritium into RNA and protein. Applied and Environmental Microbiology 56:1245-1254.

D. M. Karl, A. M. Brittain, B. Tilbrock, (1988). Initial microbiology and chemical investigations of Pele’s vent, Loihi Seamount. NOAA Symp. Series. for Undersea Res.6, 2.

S. Ramayya, A. M. Brittain, C. DeAlmeida, M. J. Antal, (1988). Acid-catalyzed dehydration of alcohols in supercritical water. Fuel 66, 1364-1371.

M. J. Antal, A. B. Brittain,  and C. DeAlmeida, (1987). Heterolysis and homolysis in supercritcal water, in supercritical Fluids, ACS Symposium Series 329, edited by Squires, T. G. American Chemical Society, Washington D. C.

M. J. Antal, A. M. Brittain, C. DeAlmeida, S. Ramayya, (1986). Catalyzed and uncatalyzed conversion of cellulose biopolymer model compounds to chemical feedstocks in supercritical solvents. Proceedings of the IGT conference on energy from biomass and wastes. Washington D. C.

C. E. Folsome, A. B. Brittain, M. Zelko, (1983). Photochemical synthesis of biomolecules under anoxic conditions. Origins of Life 13, 41-48.

C.E. Folsome, A. M. Brittain (1981). Model protocells conduct a UV photochemical reduction of carbonate to organic carbon. Nature 291,482-83.

C. E. Folsome, A. M. Brittain, (1981). Hydrazines and carbohydrazides produced from oxidized carbon in earth’s primitive environment. Nature 294, 64.

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Presentations

Obenhuber, D.C., R.L. Newton, Brittain A., Cotton H. (1998 May). Remote Interactive Experiments for Students using Virtual Instrumentation via the Internet. Post presented at 96th Annual Meeting of the American Society for Microbiolgy. Atlanta.

Brittain, A.M. (1996 November). Diversity Libraries. USCD Connect Conference, San Diego, CA, USA.

Brittain, A. M. (1996 May). A Spacecraft as A Closed Ecosystem: Theory, Reality, and Testbed. Invited talk at the 96th Annual Meeting of the American Society for Microbiolgy. New Orleans.

Brittain, A. M., Noever, D. A., Cronise, R. (1996 April). Advanced artificial intelligence methods for forecasting CO2 fluctuations in the Biosphere II gas phase. Institute of Ecotechnics and the Linnean Society 4th International Conference on Closed Ecological Systems. In London, England.

Brittain, A. M., Shaffer, J. A. (1996 April). Closed ecological systems, experimental models to study very complex systems: Linking thermodynamics, information theory and biology in vitro. Institute of Ecotechnics and the Linnean Society 4th International Conference on Closed Ecological Systems. In London, England.

Brittain, A. M., Noever, D. A., Matsos, H.C., Baskaran, S. (1996 April). Effects of Variable Biome Distribution On Global Climate. Poster to be presented at the 7th Global Warming International Conference and Expo.

Brittain, A. M. (1995 March). Ecosystems, Closed Ecosystems  and Thermophysics. Invited talk to the Geography and Environmental Sciences Department, Boston University.

Obenhuber, D. C., Brittain, A. B. (1995 January). Re-isolation of a defined microbial community from a 4 year old materially closed ecosystem. Poster presented at the Spring 1995 American Society for Microbiology meeting in Washington DC.

Brittain, A. B. (1995 January). Planet of Life Episode 9, Creatures that play god. Taped interview segment for Nippon Broadcast Company documentary on Origin and Evolution of Life.

Brittain, A. M., Shaffer, J.A. (1994). The niche for biosphere science: A research agenda for a thermodynamic approach to closed ecological systems. Conference Presentation to the 2nd International Conference on Life Support and Biospherics. University of Alabama Huntsville, Alabama.

Brittain, A. B. (1994) The steady state behavior and variability of closed ecosystems. Conference Presentation to the 2nd International Conference on Life Support and Biosphere Sciences. University of Alabama Huntsville, Alabama.

Brittain, A. M. (1994 September). Closed ecosystems, thermodynamics and space flight. Speaker for the Monasano Engineers Annual Meeting. Decatur Alabama.

Brittain, A. M. (1993). Characterization of genetically unlinked cold-sensitive suppressers of the latest acting G! cell division cycle mutation known in baker’s yeast (cdc7). Presentation at the 1993 Big Island Science Conference. Big Island, Hawaii.

Brittain A.M. (1991). Are Materially-Closed Energetically-Open Ecosystem Useful Models of Natural Ecosystem? Paper presented NASA GSRP Conference, Washington D.C.

Brittain, A. M. (1991). Greenhouses in the Sky, Closed Environment Life Support Systems. Invited talk for the Hawaii Space Society.

Obenhuber D. C., Shaffer J. A., Brittain A. M., E. B. Rogers. (1991). Closed ecological systems as models for long-term life support systems. American Society for Gravity and Space Biology, Seventh Annual Meeting.

Brittain, A. M. and Karl, D. M. (1990). Evidence for thymidine catabolism in natural microbial ecosystems. Presented at the American Geophysical Union 1990 Ocean Sciences Meeting (invited paper).

Brittain A. M. (1990). Determination of the gas exchange capabilities of a complex microbial ecosystem for use in bioregenerative life support systems. Poster presented at NASA GSRP Conference, Washington D.C.

Brittain, A.M. (1989). Stability and effects of perturbation on materially-closed energetically-open ecosystems. Poster presented at NASA GSRP Conference, Washington D.C.

Brittain, A., Shaffer, J. A. and the late C. E. Folsome. (1989). Closed ecosystems exhibit functional heterogeneity 5 years after closure. Presentation at Spring 1989 American Society for Microbiology meeting.

Shaffer, J. A., Brittain, A. and the late C. E. Folsome. (1989). A comparison of closed ecological ecosystems and open microcosms;  as measured by carbon production and biomass. Presentation at Spring 1989 American Society for Microbiology Annual meeting.

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Courses

BIOL 3050     Genetics

BIOL 4940     Biology Seminar

BIOL 2050     General Biology I

BIOL 2051     General Biology I Lab

BIOL 2052     General Biology II

BIOL 2053     General Biology II Lab

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